This is a new example and it may contain bugs. It was developed by Hoang Tran. Damage analysis was developed by Le Tuan Anh. If you find a bug, please contact IRSN: yann..nosp@m.perr.nosp@m.ot@ir.nosp@m.sn.f.nosp@m.r or carme.nosp@m.n.vi.nosp@m.llagr.nosp@m.asa@.nosp@m.irsn..nosp@m.fr
The dnadamage1 example shows a simple way to simulate dna direct and indirect damages using the Geant4-DNA physics and chemical processes in a molecular DNA geometry. Moreover, a clustering algorithm is introduced to demonstrate how to extract SSB, DSB (simple, complex).
This example is based on the work described in Sc. Rep. 7 (2017)11923 and is provided by the Geant4-DNA collaboration.
Any report or published results obtained using the Geant4-DNA software shall cite the following Geant4-DNA collaboration publications:
The geometry is chromatical fiber in a 40-nm side cube (Voxel<straight>) made of liquid water (G4_WATER material). Particles are randomly shot in a cicle of 5 nm2 radius from left side of the cube.
The DNA chromatical fiber geometry is generated by DnaFabric tool(https://bitbucket.org/sylMeylan/opendnafabric). For detail, please see: Sc. Rep. 7 (2017) 11923
The code can be compiled with cmake. It works in MT mode. Chemistry stage is automatically activated.
In interactive mode, run:
./dnadamage1
Note: interactive mode needs at least 6Go of RAM for visualization and may not work correctly in some plateformes.
In batch, the macro dnadamage1.in can be used as bellows. It shows how to shoot different particle types and energies.
./dnadamage1 dnadamage1.in
This example shows:
This example shows:
This file can be easily analyzed using the provided ROOT macro file analysis.C (and scandamges.C, molecule.C); The scandamges.C results in a text file using the SDD format: "A new standard DNA damage (SDD) data format" J. Schuemann et al. Published in Rad. Res. 191 (2019) 76-92
To do so :
Results will be obtained:
Contact: ngoc-.nosp@m.hoan.nosp@m.g.tra.nosp@m.n@ir.nosp@m.sn.fr, carme.nosp@m.n.vi.nosp@m.llagr.nosp@m.asa@.nosp@m.irsn..nosp@m.fr